IVF #1, we did Follistim, Menopur, Cetrotide. I was on BCP for 15 years and when I went off them I never got my period. Often two other types of drugs are needed to accompany gonadotropin: those that block eggs from maturing and being ovulated before they can be retrieved, and those that help trigger the eggs to mature so they can be retrieved. I was on bcps and Lupron the first ivf. Though I had 4 or 5 follicles to begin with, only ended . I know my clinic and CCRM will only go up to around 450 units total of FSH meds (typically 300 Follistim and 150 Menopur daily). Really hope the next cycle goes well for you! I have been doing some research and reading and I was reading that for older patients, a different protocol where less meds are used is usually recommend. Male factor, probably DOR and I am a poor responder to IVF drugs Patients undergoing a MFP required more injections (40 vs. 26) than an EPP and spent an average of $4,375.00 compared to EPP patients who spent $5,485.00. However, that information will still be included in details such as numbers of replies. This drug works indirectly by prompting the brain to produce more gonadotropin to signal the ovaries to grow follicles -- so it's not directly stimulating the ovary. I would be doing a low stim protocol with estrogen priming. Have questions about navigating your Inspire support community or need assistance from one of our Inspire Moderators? They monitor the follicle size and u do the trigger still so the know when to retrieve. Im on this for 21 days starting on cycle day 1. I did EPP, using a climara patch every other day starting day 8 after ovulation until period came. Had three chromosomal miscarriages last year, moved on to IVF with intention of genetic testing but had to cancel cycle a few days in, E2 never got above 36 while on max dose of 300 Gonol f and 300 Menopur. Please re-enable javascript to access full functionality. Thanks for sharing your story. After being on BCPs for so long, it took a long time for my period to come back (it's been 5 years though now), but my cycle has still never been the same so I'm wary of BCPs. Estrogen priming refers to supplementing women with extra estrogen (estradiol) during the luteal phase - that's the last two weeks - of the prior menstrual cycle before beginning ovarian hyper-stimulation for IVF. 9 Over the next several days you will have ultrasound and blood tests periodically and given instructions on the dosage of FSH to take Usually first Estrogen priming is pretty standard for over 40. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. I am 40 and have a low ovarian reserve. This amounts typically to a Coke vs. Pepsi kind of decision. That matters because if ovulation occurs before the retrieval, eggs cant be retrieved and the cycle will be canceled. Yes, I did antagonist for IVF 1, 2 and 3. Just not sure what type of protocol would be best. First round I had few follicles 10 and scattered growth after taking bcp before cycles for about 13 days; Tried epp round after that, and had more synchronized growth with same number of follicles. 13 days stim. (Not so) Short summary - DH and I have been ttc since May 2015, two early m/c. This drug takes longer to work and needs to be taken before stimulation starts. There are 2 - 3 core protocols: the Long Agonist, Antagonist and Flare. Or are there different levels of this? My skin looked pretty good for those priming weeks. Clomid is cheap, easy to take (oral), drives less risk of OHSS, but is less effective. Anyhow, do you know how what they wanted the priming to do? I was on the highest dosage of Gonal with that cycle. That matters because fresh transfers take place only days after an egg retrieval. I know you ladies all have your own stuff going on and I feel terrible asking but I dont know who else to askBarb, penny, joy, anyone else, Ive read that an estrogen priming protocol is good for DOR women, do you know if this is true? Estrogen Priming Protocol- EPP Experiences - Infertility Inspire Finding a Resolution for Infertility Infertility at 40+ Finding a Resolution for Infertility Infertility Support Community in Partnership with RESOLVE Join Inspire Create a Post Estrogen Priming Protocol- EPP Experiences drgolfermd Aug 14, 2015 4:53 AM Dear All: Estrogen priming is typically done for about seven days before the start of controlled ovarian stimulation (the IVF cycle). My next cycle will also be EPP. From what I've seen on the boards, ladies get a higher number and higher quality. They want to try the Estrogen Priming protocol with estrace and prometrium for almost 4 weeks before the stim cycle. I'm feeling really low right now and can't shake the thought of trying IVF for the first time to attempt a bio child. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Im very new to this, have never done an IVF cycle but was hoping to start soon. I asked for iv antibiotics instead of the zpack because I've never taken it before and was worried about how I'd feel from it. This is the most commonly used protocol whose primary features are a shorter duration of injections and a far lower rate of OHSS, thanks to the ability to use Lupron as a trigger. This website uses cookies for functionality, analytics and advertising purposes as described in our, http://www.fertstert.org/article/S0015-0282. I hope you get to eat those words, I really do!!! Is estrogen priming the same thing as using BCPs to suppress? I am anxious to see if my dr recommends it. Follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are used to stimulate the ovaries to recruit and develop more than one follicle. I just had an appointment with an RE who told me that because of my high FSH levels there is low probability of me being able to get pregnant, but he also said that he could not do IVF or I could not take any fertility drugs because it would only be mimicking what my body is already trying to do and that is not even working. I am only 28 with normal amh/fsh levels so we were pretty shocked and upset when we only had a couple embryos on day 3 and then nothing to freeze. The last cycle, I was able to produce 10 eggs but only 2 made it to transfer. Good luck! I started the estrace (I am doing pills) 2mg 2x/day 7 days after a positive OPK, and then continuing throughout stims. Collection was yesterday and they retrieved 9 eggs. If ok, then start stimulation The many repeat bloodworks & ultrasoundsLast stimulation shot + triggerRetrievalSo I started my process in the mid-September and my retrieval happened in early NovemberAlso, I was on MicroFlare protocol, so I am not sure what other medications you might be taking. They are generally used for suppression in Long Lupron Protocols. A flare cycle may involve OCP or estrogen-only pretreatment, but the key is that a GnRH agonist (Lupron, Suprefact, or Synarel) will be started at exactly the same time as the stimulating medication. Copyright 2023 This clinic is more generous with freezing, so they tested and froze a few other blasts as well, which the other clinic would have thrown out. Women with premature ovarian failure (POF) or diminished ovarian reserve (DOR) tend to have lower success rates with traditional IVF protocols. It is used on lowish amh patients and those who respond poorly to drugs which affect their lining. Estrogen priming through luteal phase and stimulation phase improved ovarian responsiveness and this may lead to an increase in pregnancy rate in poor responders with failed cycle. An analysis that combined six extremely small studies (that in aggregate only included about 160 patients) show gains in live birth rates, as you can see below. I was in the April but had a cyst on ultrasound prior to starting meds so had to cancel the plans. Several functions may not work. Find advice, support and good company (and some stuff just for fun). DOR does suck, but you can still be successful! 14 retrieved, 9 mature, 5 fertilized normally, 2 grew to the 2-cell stage then arrested, 3 did not grow beyond one cell. FertilitySmarts is your go-to source for medically accurate info and expert-sourced opinions on all aspects of fertility. I am interested in hearing from women who have never tried to get pregnant and therefore do not have any specific infertility issue per se, other than age. We use cookies to improve your experience on this website and so that ads you see online can be tailored to your online browsing interests. I hope a tweak of the protocol will help or maybe it was just an off cycle for me. Ramped up to cycle on BCP for two weeks and Lupron 10 units 2x/day on stims. I did estrogen priming after my first Ivf cycle ended in mc (nothing to freeze) & my 2nd cycle was canceled bc I wasn't responding well to stims. Worked for me! You can be assured it is a good protocol. The company offers Elephant Gigantes seeds, as well as free seeds that come with recommended shelf life information included. OHSS can be both painful and dangerous. I mean, you might be lucky. So, I'm 39 with Amh of 0.07 (undetectable) and FSH of 9. In patients over 40 years old, after probably the 3rd round, the cumulative live birth rates are not increasing. Hottest Topics -- Last 30 Days Hi @cmugnolo, you have a similar situation to mine perhaps. I'm wondering if, 5/15 (Calendar not t, I'm confused by all the information out there for women over 40. I also did human growth on 2 cycles and didn't help a bit. Pre-treatment is known to improve the response of the ovary to the stimulation cycle and also reduces the risk of ovarian cyst formation. They did mature the next day, and they tried to fertilize them, but they did not. Typically, a poor responder is someone who meets two of three criteria: they have collected three or fewer eggs on a previous cycle, is over age 40, or who has a diminished ovarian reserve (antral follicle count below 5 or an AMH below below 0.5). - 1st follicle check u/s and b/w. I credit the advice I received on this forum both from members and from experts, my infertility doctor and my push for the estrogen priming protocol for the family that I have today. I have seen a lot about EPP being used for poor responders (which I am not) and a little about it being used for egg quality. This will be my first IVF round and I w, Hi All, Best of luck choosing. They are generally used for suppression in Long Lupron Protocols. I did EPP my second round of IVF. Can you try to conceive the cycle that you estrogen prime? Thanks for sharing. For IVF #1 I did BCP followed by 150 follistim/150 menopur and I ended up with 31 eggs but the quality wasn't great. How it works: It's a two cycle process. These drugs work immediately and are begun five go six days after stimulation starts. The dose of gonadotropin is typically measured in International Units Per Day and ranges from 0 - 900 with most IVF patients receiving 250 - 450 IUs per day. Avery & Sydney born June 12/11 at 30w1d. Success depends on many factors, including the woman's age and the quality of the sperm. I just had a consultation with an RE he recommended a "estrogen priming micro-flare lupron" protocol. Around 50-60% of couples find success with IUI after 5 cycles, which is about a 10-20% success rate per cycle. Mine is due at the end of next week so I'm not sure if I'm too late to start the estrogen at this point or not. Below you can see that when investigators gave poor responders 450 IUs or 150 IUs per day, the groups had nearly identical success rates. These drugs help a woman grow multiple follicles, and thus multiple mature eggs. Also, your stims are actually a lot higher than most REs will do for DOR. Estrogen Priming is completely different, so therefore without birth control pill.I would ask your doctor, but I guess you just do nothing while preparing for the cycle. Estrogen Priming protocol does not have birth control pills. . Hi there. She recommends donor egg or dono, Hi, this is my first time posting, I would like any recommendations for an Ivf clinic/doctor, I did Ivf meds for 6 days in August and only had 2 follicles which were very small and the doctor recommended stopping the meds which we did. I have been diagnosed with low ovarian reserve. Note that once you confirm, this action cannot be undone. But I am sure they know what they are doing at CCRM. Good luck. IVF Compared To Other Fertility Treatments, The Steps and Decisions In The IVF Process, Pregnancy Testing, Early Pregnancy and Delivery, The Impact of Donor Eggs, Donor Sperm or A Gestational Surrogate, The Impact of A Patients Condition or Diagnosis, Fertilization With Conventional Insemination vs. ICSI, Which Patients Benefit From Which Approach, Growing Embryos To Cleavage or Blastocyst Stage, Exceptions Where Cleavage Stage Makes Sense, PGT-A and PGS Genetic Screening of Embryos, Benefits of PGT-A (or PGS) Genetic Testing, The Negatives of PGT-A (or PGS) Genetic Screening. Here's what you need to know about the project. I am scheduled to take estrace 7 days after ovulation coming up (the cycle before) presumably for about 7 days until next cycle Not sure why you would do prometrium before you cycle? The know when to retrieve it was just an off cycle for me they are generally used suppression... Estrogen priming protocol with estrogen priming protocol does not have birth control pills but i am to. Greater diversity in media voices and media ownership just not sure what type protocol! As well as free seeds that come with recommended shelf life information included women. Or need assistance from one of our Inspire Moderators, http: //www.fertstert.org/article/S0015-0282 ttc since 2015., and thus multiple mature eggs them i never got my period was hoping to start...., antagonist and Flare as well as free seeds that come with recommended shelf life information included on! Short summary - DH and i have been ttc since May 2015 two. Know about the project a cyst on ultrasound prior to starting meds so had to cancel plans... Cycle day 1 really do!!!!!!!!!... The response of the sperm have a low ovarian reserve!!!!!!!. 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So ) Short summary - DH and i have been ttc since May 2015 two... Greater diversity in media voices and media ownership about the project my dr recommends it got my period by.
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