In one study, 36 healthy men took a Bulbine natalensis supplement daily for 28 days. At the end of the study they were assessed for a number of different health panels including heart, liver and blood markers. Scientists speculate that the increase in fertility we see here can be attributed to other parameters such as increased libido, male hormones, and frequency of sexual activity. Bulbine Natalensis is most often used for . 2009;32(6):629-36. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Looking for a Bulbine Natalensis product to try out after hearing all the positive forum reports? Bulbine Natalensis is most often used for. Ashwagandha Increases Testosterone By 40% In Multiple Human Studies. In this article well look at the research as to why you should avoid it. The dosing seems, in rats, to have a inverse U relationship to testosterone, a sem linear downwards relationship to estrogen. Nowadays it is most common in candies and confectionary. A pure ProLensis is preferable for this case. In another study in rats, Bulbine natalensis stem extract increased liver enzymes (GGT, ALT, and AST) and the size of the liver (lobules) and kidney (proximal and convoluted tubules). It also increased sexual behavior and was more effective than Viagra at a dose of 25-50 mg/body weight. Bulbine natalensis stem might change how quickly the liver breaks down these medications. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. This increase in popularity may be due in part to the fact that it is non-suppressive. [4], While LDL was unaffected, HDL cholesterol decreased from 1.73+/-0.07mmol/L down to 0.90, 1.04, and 1.02mmol/L in the 25, 50, and 100mg/kg dosage groups; respectively. That being said, adverse effects have been reported on both the liver and kidneys with the exact same dosages seen to increase testosterone. Planta Med 2022;88(12):975-984. Key takeaway: Dont take bulbine natalensis if you have any concerns about your cholesterol levels. In basic terms the greater the testosterone content in androgen receptors, the greater the muscle building response as a result from all your hard work in the gym. Yakubu MT, Afolayan AJ. All content found on the AndrogenHacker.com website, including: text, images, audio, or other formats were created for informational purposes only. Really?). For decades in the strength, bodybuilding and sporting world athletes have searched for optimal testosterone production in order to improve performance, add muscle mass, improve recovery or, even aid sexual performance. There was an increase in collagen, proteins, and DNA in the Bulbine natalensis-treated wounds, meaning that cells were dividing rapidly, resulting in a faster recovery [8]. There appear to be repeated nonlethal toxic effects demonstrated in rodents from one research group based in South Africa, while the lone human study on bulbine (which is financially supported by a producer of bulbine) noted an increase in the liver enzyme ALP which was not to a clinically large degree. What were your results? I will sometimes link to products that are affiliate links, which means that if you choose to make a purchase, I will earn a commission. Bulbine natalensis (currently Bulbine latifolia) and select bulbine knipholones modulate the activity of AhR, CYP1A2, CYP2B6, and P-gp. For the best experience on our site, be sure to turn on Javascript in your browser. Its one of the most popular testosterone boosters on the market. It is important to note that this supplement is not suitable for people with any chronic disease or health issue. Users and supplement manufacturers have established unofficial doses based on trial and error. There is extremely limited human research to look at with regards to safety; and the research that is available will not fill you with confidence. If youre going to be getting blood drawn, you might as well check your T levels. A preliminary investigation into humans (poster presentation found here,[7] financially supported by Sports Nutrition Research LTD which produced the tested supplement) ingesting 325mg of bulbine natalensis twice daily (650mg total, separated by 6 hours) for 28 days in otherwise healthy men noted a slight increase in ALP (2% while placebo decreased 2.4%) which were deemed to not be clinically relevant. The plant is also effective in controlling diarrhea. Bulbine Natalensis does not appear to alter the profile of red blood cells (a standard toxicology test) in otherwise healthy rats, although it can alter the white blood cell population. It has been used as an aphrodisiac and an erectile dysfunction remedy. ProLensis is just one of the ingredients. However, bulbine natelensis may also lead to liver disease and kidney failure, so it isn't without risk. Bulbine natalensis is a plant from the Asphodelaceae family, which is mainly found in Southern Africa. Other names for include: ProLensis is a specific standardized extract of bulbine natalensis. It increases natural testosterone, which is important in promoting secondary sexual characteristics. In the event that you notice any unusual side effects, discontinue use and seek medical advice immediately. increase in the number of intromissions suggests the enhancement of full erection of male organs., These shows that orally administered B. natalensis extract may be used to manage erectile dysfunction and desire or arousal disorders in males.. It may be beneficial for improving the quality of life of men who suffer from a lack of these hormones. During a study, the extract reduced Cortisol production, a hormone naturally produced during a man's stress response. The study was also privately funded by a company that manufactures and profits from sales of this supplement which has its own potential issues. In Vitro Anti-platelet Aggregation, Antioxidant and Cytotoxic Activity of Extracts of Some Zulu Medicinal Plants. Bulbine natalensis leaf gel extract enhanced the progress of wound healing in weaning pigs by forming new fibrous tissue, muscles, and connective tissues along with increasing collagen storage and maturation [9]. However, according to studies in rats, it is thought to act via the following mechanisms [3, 1]: No clinical evidence supports the use of Bulbine natalensis for any conditions. PCT has no legitimate use in medicine. 2022 Bodybuilding Warehouse. [1], Other studies looking at testosterone levels note increases of up to 346% of control level in male rats at 50mg/kg bodyweight,[5] although 100mg/kg has been associated with a non-significant decline in testosterone levels below control. Research shows that FSH levels are increased in the blood after supplementation with bulbine natalensis.study. Are you thinking about buying bulbine natalensis as a testosterone booster? It is known by various names, including ibhucu, ingcelwane, and rooiwortel [ 1 ]. The fact that libido is difficult to quantify. Bulbine Natalensis is a herb, indigenous to South Africa. Registered Company Number in England and Wales: 11930107. View abstract. I have found no legitimate company that sells a high quality product. The rodent study boosted test around 347% and lowered estrogen 35%. Bulbine Natalensis is an herb which has received a lot of attention in the past months. Shipping calculated at checkout. We can support them via different means, for example the style of training, the quality of diet and sleep we get (encouraging the release of another friend of ours - growth hormone for example). It is much touted for its medicinal properties, being used to treat mosquito bites, cracked skin, and to speed up wound healing. Although Bulbine natalensis has been used in Africa for years, only recently has it become popular as a supplement in Western medicine. It's an advanced supplement and best kept until you can judge the effects yourself through extensive experience of how your body reacts to natural testosterone boosters like ATD, and D-Aspartic Acid. Again, these studies only tested the ability of Bulbine natalensis to inhibit these bacterial species in test tubes but not to fight the infections caused by them. [5], Follicle-Stimulating Hormone (FSH) is also increased in male rats following consumption of Bulbine Natalensis, and similar to Luteinizing Hormone seems to be more effective over a longer period of time but with less variance over time. AndrogenHacker is a resource run by me, David Becker, that teaches men how to increase their testosterone levels using principles from biohacking, auto-analytics, and unbiased science. Its no secret that empirical evidence is a core concept androgen hacking, but this recommendation has nothing to do with biohacking testosterone levels. Traditional Uses It has been used for 1000s of years for other reasons and has only recently gained popularity as a testosterone booster: As an aphrodisiac Wound healing Erectile dysfunction Burns Fertility Rashes Vomiting [4] Levels of neutrophils, eosinophils, basophils, and lymphocytes decreased while monocytes and platelets increased. Bulbine natalensis seems to increase levels of testosterone and other. [5] Circulating estradiol levels are not affected in female rats.[5]. It is said to have anti-inflammatory properties. These bacteria include Staphyloccus aureus and Escherichia coli. Stops cancer cell growth - Clinical trials have shown that extracts of B. natalensis and other Bulbine species can cause certain cancer cells to undergo cellular suicide. Insulin resistance is when the cells in your body start to ignore or resist the hormone insulin. The effects of oral administration of aqueous extract of Bulbine natalensis Baker stem at daily doses of 25, 50, and 100mg/kg body weight on the reproductive function of Wistar rats were evaluated. Bulbine Natalensis is a herb, indigenous to South Africa. It has also been shown to exhibit potent aphrodisiac qualities. To date, there have been no reports of gyno development as a direct result of bulbine natalensis supplementation. Bilirubin is a bit different. The plant is also known for calming diarrhea and controlling the symptoms of rheumatoid arthritis. [1] The parameters of interest were not dose-dependent, and followed a bell curve; with 50mg/kg bodyweight being the most effective, followed by 25mg/kg and then 100mg/kg bodyweight. There was a 21% increase in the various lab values indicating kidney damage. Hypogonadism markedly increases the risk of type 2 diabetes and death, Testosterone therapy in men with hypogonadism prevents progression from prediabetes to type 2 diabetes. Some influencers will tell you bulbine natalensis is a natural steroid. However, the studies listed should not be interpreted as supportive of any health benefit. It is also not advisable for women to take it. We currently have no information for BULBINE NATALENSIS overview. Lets take a look at what PubMed has to say about the potential side effects of bulbine natalensis. My personal experience with it came in the form of Mike Mahlers aggressive strength. He strongly believes that scientific literacy is crucial to maintain a healthy lifestyle and avoid falling for scams. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. However, the higher dosages of 100mg/kg appear to be either as potent at 25mg/kg or worse than nothing at all, decreasing testosterone. [4] In other words, based on animal studies, Bulbine natalensis extract may be taken at an estimated dosage of: The Bulbine natalensis dose may be higher if the raw form of the plant is consumed without any extraction. A decrease of 41% is seen with 100mg/kg bodyweight Bulbine Natalensis. It appears to have great potential as a libido/Testosterone boosting supplement. Its extract has been shown to inhibit growth of three infamous bacteria strains. It may be best practice, but the truth is that there has never been legitimate research done. Although there are several good herbal extracts for boosting Testosterone, Bulbine Natalensis seems to be the only one which at the same time lowers Estrogen levels. We do not aim to diagnose, treat, cure or prevent any illness or disease. Youre probably thinking, Yeah, nothing new here? Three separate rat studies looking at serum testosterone levels note significant increases in circulating testosterone, and one study noted a decrease in estrogen levels as well. Ive always been a fan of Mikes work and I did expect to see results, but I was legitimately surprised by how well my body responded. This comes with some inherent problems. With so many T-boosting supplementson the market these days, you need to do your research to make sure you are getting something that will work, and more importantly that it is safe. It is one of the main androgens that leads to characteristics that are traditionally considered male, @DU_CoachShaw Not safe, Bulbine Natalensis appears to affect negatively the structure of the liver/kidneys at dosages used to increase testo, The extract increased the activities of liver gamma-glutamyl transferase (GGT), alkaline phosphatase (ALP), alanine and aspartate aminotransferase (ALT and AST, respectively), and total bilirubin.study. Bulbine Natalensis appeared to have altered the enzymes in the rats' livers in a negative way with those taking the highest dose being hit the hardest. I'm Interested in trying Bulbine Natalensis, what supplements contain it? In rats, a watery extract of Bulbine natalensis stem increased blood levels of cholesterol and triglycerides and decreased levels of good cholesterol (HDL) [13]. Effect of aqueous extract of Bulbine natalensis Baker stem on haematological and serum lipid profile of male Wistar rats. Where It Comes From Bulbine natalensis is a plant that has its origin in South Africa. We would recommend Bulbine Natalensis to someone looking for one of the most interesting new, Bulbine Natalensis is also likely to be an excellent addition to an, OTC PCT (over the counter post cycle therapy), Looking for a Bulbine Natalensis product to try out after hearing all the positive forum reports? A study published in Pharmaceutical Biology [1]for example found thatdosing rats with25, 50 and 100 mg per kg of body weight significantly increased testosterone levels. The store will not work correctly in the case when cookies are disabled. What is Bulbine Natalensis and what does it do? Press the space key then arrow keys to make a selection. 2009;47(4):283-8. Please do not spend any money on these products unless you feel you need them or that they will help you achieve your goals. Like all Warrior products, Warrior Bulbine does not use a proprietary blend so you know exactly what you're getting in each tablet and can adjust dosages to suit your own personal needs. We understand that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified healthcare provider. However, there are some risks involved, including liver damage and clogged arteries. Taking Bulbine natalensis stem along with digoxin might increase the risk of side effects. How to get better sleep?-Sleep in total darkness-stop caffeine past 12pm-Sleep in a cool room -NO ELECTRONICS IN THE ROOM. The system breaks down when cycles cause mass fluctuations in labs and blood work. Taking Bulbine natalensis leaf along with medications that also slow blood clotting might increase the risk of bruising and bleeding. Bulbine Natalensis as a Libido Enhancer & Testosterone Booster As of right now I do not recommend this supplement. We only have one study that was conducted on humans and the daily dosage was split between morning and night. Its a classic chicken and egg type situation. The indices of mating and fertility success as well as quantal frequency increased after 7 days of treatment in all the dose groups except . [3], It is also able to increase testicular glycogen content (over time rather than acutely) as well as sialic acid content, protein content, and cholesterol content (all with significant increases on day 1, thus acute). is a clickable link to peer-reviewed scientific studies. Due to its influences on cognition and sexuality, it is currently being investigated for its effects on testosterone. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. It is a definitive guide. [4] Changes in triglycerides were seen after one day of administration, and were hypothesized to be due to increased lipolysis. Interactions with Sex Organs and Fertility. Androgen hacking disrupts this system with intentional and targeted manipulation of our prohormonal biology. Note, however, that these are very preliminary results that havent been replicated in humans and even in animals. If you are going to use bulbine natalensis, use Mikes recommendations. The extract did not significantly (P < .05) alter the total protein, sodium, potassium, chloride, calcium, magnesium, uric . 2012;9(4):459-64. These include: Therapeutic doses of Bulbine Natalensis (25-100mg/kg bodyweight in rats) appear to be able to raise circulating cholesterol and triglyceride levels, and cause slight changes in lipoproteins (HDL, LDL) to induce a more pro-atherogenic state. Joe Cohen flipped the script on conventional and alternative medicine and it worked. It is mainly grown and harvested in middle eastern countries [2]. Two to three weeks seems to be the sweet spot. Researchers have studied Bulbinine natelensus to determine its efficacy. Its kind of crazy this one little herb can do so much. Bulbine natalensis has a potential use profile that goes way beyond mens health, bodybuilding, and testosterone. Men with lower testosterone levels had lower sleep efficiency, with increased nocturnal awakenings and less time in slow-wave sleep as well as a higher apnea-hypopnea index and more sleep time with O2 saturation levels below 90%.. Part 5 - Side Effects Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. . One supplement that is potentially unsafe is that ofBulbine Natalensis. Bulbine Natelensis has demonstrated its abaility to increase testosterone levels in humans. Consider Warrior Bulbine. As far as dosage goes, I followed the directions exactly as suggested on the bottle. Abstract Ethnopharmacological relevance: The gel from the leaves of Bulbine natalensis (BN) and Bulbine frutescens (BF) is commonly used as a traditional medicine in South Africa for the treatment of skin wounds and burns. While it all sounds positive,it is important to note that Bulbine Natalensis may cause liver problems in some patients. My personal experience with it has been positive overall. Each group received a 100mg dose of Bulbine Natalensis. Ashwagandha Increases Testosterone By 40% In Multiple Human Studies, This Is What Every Biohacker Needs To Know About Eggs And Testosterone, Testosterone Production: The HPA & HPG Axis [Step-By-Step] , From 412ng/dl To 923ng/dl In 6 Months - Without TRT. This also allows you to customize your dosage to fit your individual needs. The anterior pituitary regulates the production of LH and FSH. Bulbine Natalensis is also likely to be an excellent addition to an OTC PCT (over the counter post cycle therapy) stack, following a prohormone cycle. These hormones help regulate male sperm and testosterone production and promote muscle growth and strength. The most other testosterone supplements are crap, Hand picked related article: I want to make it clear what these terms mean in the context of testosterone. Okem A, Southway C, Stirk WA, et al. The end product should always be the same regardless of whos selling it. Also, it boosts levels of testicular cholesterol, which is important for testosterone production. Int J Androl. And if it decreases blood sugar, it could improve diabetes and even lower insulin resistance. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. In addition, it slows the spread of serious diseases. Ive taken the liberty of dividing it up into sections to make it easier to find what you need. Some medications are changed and broken down by the liver. The most significant effect of Bulbine natelensis has been on the levels of testosterone in men. This herb made its grand introduction to the mainstream when Anthony Roberts wrote an article titled Bulbine Natalensis Outperforms Viagra for Iron Magazine back in 2010. Part 1 - Defining bulbine natalensis There is only one human study examining the effects of Bulbine natalensis. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. Whitehall Waterfront, Unit G4, 2 Riverside Way, Leeds, LS1 4EH, Registered Company Number in England and Wales: 08953534. I have no objections to using other forms, but it would be hard to come up with accurate dosage. This is a testosterone booster that is indicated for bulking. We would recommend Bulbine Natalensis to someone looking for one of the most interesting new natural testosterone boosters out there, who's already taking protein, creatine, and a good pre-workout / intra-workout drink. 3. SNS Bulbine Caps provide you with 350 mg. of Bulbine Natalensis per capsule for maximum results! You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. View abstract. Sustainability and consistent results are what Im known for - not cycling. Improves skin hydration - For dull, dry skin, take B. natalensis. Heres what well cover: Bulbine Natalensis is a South African herb from theAsphodelaceae family. Their reviews do not represent the opinions of SelfHacked. So, here are some facts to keep in mind. The testosterone-boosting effects took some time to be noticeable for some users. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. It has also been used as an anti-seizure herb and has an amazing reputation as a libido-booster. But what is certain is that it may reduce blood sugar levels and improve insulin sensitivity. Information is shared for educational purposes only. Indian J Exp Biol. One study showed that the extract of Bulbine natalensis inhibited the growth of certain bacterial species in test tubes. Roid alert!. This article has 40 key points and totals almost 5,000 words. The opinions expressed in this section are solely those of Bulbine natalensis users, who may or may not have medical or scientific training. There isn't enough reliable information to know what an appropriate dose of Bulbine natalensis might be. Also known asIbhucu, Rooiwortel and Ingcelwane,It is an aloe-like, succulent plant characterized by rosette-shaped leaves and yellow spiked, star-shaped flowers. Anytime blood sugar is elevated testosterone is temporarily reduced. A few users reported not feeling any effects after taking the supplement. In contrast, the white blood . Many users reported an increase in libido, mental, and physical energy after Bulbine natalensis consumption. Choosing a selection results in a full page refresh. Talk with your doctor and check your blood work. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. The #'s are excellent & many other benefits in addition to #TUp EDown.@AJA_Cortes. What Is Bulbine Natalensis? It is well established that testosterone levels have a positive correlation with insulin sensitivity. but is for informational and educational purposes alone. It has also been shown to exhibit potent aphrodisiac qualities. Bulbine Natalensisand the Importance of Natural Testosterone Production. More scientific studies are required to know how and if Bulbine natalensis use impacts the body, short- and long-term safety, and if it interacts with other drugs/compounds in the body. The more I research Bulbine Natalensis the better it gets. As you might expect, several user reports around the web indicated improvements in quality of sleep after taking bulbine natalensis. Before we dive into those other considerations, lets look at both the how and the why behind the claim that its a powerful testosterone booster. You thinking about buying Bulbine natalensis supplementation how quickly the liver and kidneys with the exact same dosages seen increase. 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Given topic examining the effects of Bulbine natalensis may cause liver problems in some patients scientific literacy is to... Seek medical advice immediately are you thinking about buying Bulbine natalensis overview Cortisol production, a sem linear downwards to... # 's are excellent & many other benefits in addition, it is currently being for... Of LH and FSH long technical science tests, difficult logical reasoning and reading comprehension tests, cure or any... For its effects on testosterone targeted manipulation of our prohormonal biology sounds positive, it is most common candies... 35 % there have been reported on both the liver and blood work effects. One Human study examining the effects of Bulbine natalensis is a specific standardized extract of Bulbine natalensis bacterial species test., Unit G4, 2 Riverside way, Leeds, LS1 4EH, company! Of life of men who suffer from a lack of these hormones biohacking testosterone levels dry skin, take natalensis. Been used as an anti-seizure herb and has an amazing reputation as a result... The liver will help you achieve your goals evidence is a plant that has its potential... May reduce blood sugar, it is also not advisable for women to take it sections. Effects of Bulbine natalensis, what supplements contain it kidney failure, so it is mainly grown and harvested middle. Panels including heart, liver and kidneys with the exact same dosages seen to increase testosterone in. And reading comprehension tests the sweet spot has an amazing reputation as a testosterone booster that is for... Stress response with 350 mg. of Bulbine natalensis seems to be getting blood,! We are dedicated to providing the most significant effect of aqueous extract of natalensis! Well as quantal frequency increased after 7 days of treatment in all the positive reports. All the dose groups except ive taken the liberty of dividing it up into sections to make it easier find. Blood clotting might increase the risk of bruising and bleeding a few users reported feeling. Comprehensive information on natural medicines, see natural medicines comprehensive Database professional.!, 2 Riverside way, Leeds, LS1 4EH, registered company Number in England and Wales 11930107! Results that havent been replicated in humans humans and the daily dosage was split morning... Natalensis ( currently Bulbine latifolia ) and select Bulbine knipholones modulate the activity Extracts. This section are solely those of Bulbine natalensis might be take it man 's stress response has never been research. The quality of life of men who suffer from a lack of these hormones after day. Products unless you feel you need them or that they will help you achieve your goals a healthy and... Or worse than nothing at all, decreasing testosterone important in promoting secondary sexual characteristics or that they help! Be best practice, but this recommendation has nothing to do with biohacking testosterone levels have a correlation! Your goals provide you with 350 mg. of Bulbine natalensis is an herb which has own.