It is the brand name of the injection Semaglutide. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Greenway FL et al. If you take other drugs that contain bupropion. Taking Your Thyroid Medication With Meals and Snacks The synthetic thyroid hormone won't be absorbed properly unless you take it on an empty stomach and wait 45 to 60 minutes afterward. They may adjust your diabetes treatment plan. These conditions can increase your risk of seizures from Contrave. Early J, Whitten JS. If you found this article helpful, please consider following my blog, and share it with someone you know can use the help! Or they may prescribe a different treatment for you instead. Bupropion is officially used as an anti-depressant, and also helps people quit smoking. Be sure to tell them if you have these side effects while taking the drugs together. If you have questions about which foods to avoid with Contrave, talk with your doctor. So, if you prefer oral tablets and can conveniently incorporate them into your lifestyle, Metformin is a better choice. These medications are not usually taken together. When used alone, naltrexone is used to treat addiction, whereas bupropion is an antidepressant. What should I avoid when taking Contrave? Your doctor can recommend other treatment options for you. They can tell you if its safe to take these medications together. Other medications you take, as well as any vitamins, supplements, and herbs. Terms and Conditions and Privacy Policy. You should not take CONTRAVE again if you have a seizure. Also, if youre actually hungry, Contrave may not do much to reduce that hunger. Metformin has very few drug interactions but shouldnt be taken with iodinated contrast media, which is the most common interaction. They were then divided into groups that either took a combination of naltrexone and bupropion or a placebo pill. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. Diabetol Metab Syndr. If youre an emotional eater, and tend to reward yourself with food, or eat as a way to soothe negative emotions, Contrave may help you break this emotional connection with your food, and might allow you to look at food as a form of nutrition, rather than a form of comfort. (An active ingredient is what makes a drug work.) Your doctor may notice that your blood pressure or heart rate increases when taking Contrave. These conditions can increase your risk of seizures from Contrave. It may not be safe to drink alcohol while taking Contrave. Do not take Contrave if you have uncontrolled high blood pressure; have or have had seizures; use other medicines that contain bupropion; have or have had an eating disorder; are dependent on opioid pain medicines or use medicines to help stop taking opioids such, or are in opiate withdrawal; drink a lot of alcohol and abruptly stop drinking; are You can ask them about other treatments that may be better options for you. It did a number to my heart as it passed through. Naltrexone is an opioid antagonist that blocks the effects of opioid-like drugs i.e heroin. Contrave pills contain two medications. Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. This condition is a medical emergency. Its important to note that this drug can cause harm to a fetus, so your doctor may not recommend it if you can become pregnant. To learn more about their possible interactions, talk with your doctor or pharmacist. How can [], Article Contents What is metformin? On the other hand, Ozempic comes in the form of an injection which is administered once a week. It has been estimated to cause up to 16% body weight loss from the baseline. This collaboration was the first of its kind in the organization. These factors include if you take another drug that increases your risk of seizures or if you have a seizure disorder or a condition that may cause seizures. In combination, they act on two areas within the brain, the hypothalamus, and the mesolimbic system, to control the appetite and reduce cravings. A glaucoma attack may cause sudden blurry vision and eye pain. From research studies, an outline of the common and rare side effects associated with Contrave is as follows: Common side effects (reported in more than 1% of patients): Rare side effects (reported in less than 1% of patients): Its important to note that Contrave contains a combination of two medications: bupropion and naltrexone. Minimally clinically significant. This article is for general informational purposes only. Before taking Contrave, tell your doctor if you take an MAOI. But it sure had an interesting side effect of hair growth. If they tell you its safe, your doctor may lower your SSRI dosage. Should I avoid certain foods while taking Contrave? All participants have been prescribed a mildly reduced-calorie diet and exercise. Hunger is your body telling you it needs to eat, to function properly. The way Contrave works for weight loss is not entirely understood. Location: Morristown, NJ. Among all the weight loss drugs, Wegovy is considered superior. Highlights Taking these medications together could increase your risk of side effects from Contrave. 2010; 376 (9741): 595-605.5. rybelsus and jardiance together. On average, patients lowered their hemoglobin A1c levels by over 2% through working with Diana. You can also read our in-depth comparison of Contrave vs phentermine. Contrave crosses the placenta and passes into the breast milk. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527439/, 15 foods to naturally lower blood sugar levels. * Contrave has a boxed warning for the risk of suicidal thoughts and behaviors. This is because taking the drug could cause another allergic reaction. SSRIs are a type of antidepressant. Naltrexone/Bupropion (Contrave) for Weight Loss. If you need help understanding this information, your doctor or pharmacist can help. You should lose weight with phentermine, it is an appetite suppressant, but maybe you can ask your dr. about alternatives to metformin, because of your concerns. As far as medications are concerned, metformin is usually the best first option for the majority of baby boomers with prediabetes (insulin resistance). Contrave is an anorexiant drug that is used to decrease the weight of the body by decreasing the appetite of a person. You can ask them about other treatments that may be better choices for you. Ozempic vs. metformin: how do they compare? https://pubmed.ncbi.nlm.nih.gov/20673995/. Contrave is suitable for adults with a body mass index (BMI) of 30 or greater, or 27 or greater with at least one weight-related medical problem. weight loss management for an obese person, weight loss management for overweight person with bmi 27 to 29 and weight-related comorbidity. If you have high blood pressure that isnt well managed. Long story short, I developed a Massive Pulmonary Embolism in my lungs due to the contraceptives. The use of iodinated contrast dyes increases the risk of lactic acidosis.This interaction is very rare and would only happen if the contrast dye itself caused renal impairment (kidney damage). Your doctor can recommend other treatment options for you. This could increase the amount of beta-blocker in your body, which may raise your risk of side effects from the beta-blocker. Lancet. Taking Contrave in these situations can increase your risk of seizures. But this doesnt mean that interactions with herbs wont be recognized in the future. I'm new here. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Beta-blockers are used to treat high blood pressure. Talking with others can give you the motivation you need to continue. Phentermine.com is a property of: Careworld LLC. Of the total drug interactions, 2 are major, 222 are moderate, and 21 are minor. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. If you are prone to frequent or excessive alcohol use, talk to your doctor before starting buPROPion. JAMA. Wadden TA et al. Dizziness and trouble sleeping are also noted by some patients. Liver-Metabolized Drugsmay increase the effects and side effects of cyclosporineand other drugs processed in the liver by slowing down the metabolic process.17-19 Quinolone antibioticsmay reduce the efficacy of these types of antibiotics, also known as fluoroquinolones.4,10 In July of Last year I was put on birth control pills to help with my diagnoses of PCOS. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. It does not create a doctor-patient relationship between Dr. Yeung and you. Bipolar disorder. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Iodinated contrast dye can seriously interact with metformin so should be avoided. If you have type 2 diabetes, talk with your doctor before taking Contrave. Theyre used to treat conditions such as depression and anxiety. Learn how we can help 5.3k views Answered >2 years ago Thank A 49-year-old member asked: Contravehcp.com (Contrave FAQs).6. The symptoms of lactic acidosis usually set in quickly and include abdominal discomfort, fast, shallow breathing, muscle pain and cramping, and unusual fatigue. It can cause both high and low blood sugar and isnt recommended for people with diabetes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If you have severe renal impairment or kidney disease, you might also be at greater risk of developing lactic acidosis because your kidneys cant clear the lactic acid from your system. In some cases, Contrave can cause suicidal ideation. Consult with your primary care physician before combining any medications. Patients in the study may take other drugs besides Contrave and Metformin. If you do decide youd like to use it, keep in mind these 4 things: Overall, Contrave may be helpful for emotional overeaters and people with strong cravings to overcome these issues and more easily follow a weight loss diet. It is very safe as well and has a long track record. 5 8 comments Best Add a Comment 77kloklo77 1 yr. ago I was on both Wellbutrin and Ozempic for a few months last year. Moderately clinically significant. This report displays the potential drug interactions for the following 2 drugs: Applies to: Contrave (bupropion / naltrexone) and Contrave (bupropion / naltrexone). And Contrave can cause serious side effects, such as . Very rarely, a condition called lactic acidosis may occur while taking metformin. 2011; 19(1): 110-120. NSAIDs, like Aleve, can decrease kidney function and increase blood pressure. Dr. Hannah England was awarded a medical degree from The University of Sheffield and worked for several years as a doctor in hospitals and community medical settings. Many weight loss clinics use this combo. Usually avoid combinations; use it only under special circumstances. You cannot buy Contrave over the counter. It is also unsuitable for patients with high blood pressure, seizures, or a history of anorexia or bulimia. Comparison of combined bupropion and naltrexone therapy for obesity with monotherapy and placebo. You may also want to check out the online communities at Bezzy. For questions regarding your prescription medication, we recommend consulting with your doctor or pharmacist. It is created by eHealthMe based on reports of 220 people who take Contrave and Metformin from the FDA, and is updated regularly. Learn more about certain drug interactions that can occur with Contrave. This is because taking the drug could cause another allergic reaction. Here are seven places to, Body mass index (BMI) is a highly controversial health assessment tool designed to estimate a persons body fat and risk of poor health. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you take an MAOI or have taken one in the past 14 days, your doctor likely wont prescribe Contrave for you. The mechanism by which it works is unclear, but it is believed to target certain areas of the brain related to eating, such as the pleasurable sensations derived from eating delicious food or feeling full. Contrave.com (Contrave Purchase FAQs).10. Contrave (naltrexone hydrochloride and bupropion hydrochloride) extended-release tablets, for oral use. Headaches and dizziness are some of the most common issues Ive observed. Please allow 10-15 minutes for your eBook to arrive. If you have certain risk factors related to seizures, your doctor will likely not prescribe Contrave for you. That means that you can safely take metformin with other types of medication for diabetes, including insulin and sulfonylureas. If you have bulimia or anorexia or have had these conditions in the past, your doctor likely wont prescribe Contrave for you. eHealthMe is studying from 4,486 Contrave users for its effectiveness, alternative drugs and more. Both these appetite suppressants are effective for reducing food cravings and calorie intake. rybelsus and jardiance together. If you take opioids, your doctor likely wont prescribe Contrave for you. Lactic acidosis is a serious condition where your body creates more lactic acid than your body can clear. What to do if you start taking a new drug during your Contrave treatment. Hypersensitivity reactions (frequency unknown), Suicidal thoughts or behavior (frequency unknown). If youve had an allergic reaction to Contrave or any of its ingredients, your doctor will likely not prescribe Contrave. Specifically, bupropion may cause a false-positive result for amphetamines on a urine drug test. (8). Usually, they include mild to moderate gastrointestinal issues like nausea or diarrhea ( Hausner, 2017 ). Before starting treatment, talk with your doctor and pharmacist. There are currently no reports of Contrave interacting with vaccines. Minor: Interactions experienced are considered clinically minor. The health information contained here is provided for educational purposes only and is not intended to replace discussions with a healthcare provider. Contrave has active ingredients of bupropion hydrochloride; naltrexone hydrochloride. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Not only did it help her beat smoking and deal with the anxiety after effects of that, she says it also boosted her sex drive and did have appetite-reducing qualities. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. One of the benefits of metformin is that it doesn't cause low blood sugar. Theyll determine whether Contrave is right for you. If you take Contrave with amantadine, your doctor will monitor you closely for the side effects listed above. To learn more, see the When should I avoid Contrave? section above. X27 ; t cause low blood sugar used alone, naltrexone is used to treat conditions such.! Seizures from Contrave regarding your prescription medication, we recommend consulting with your doctor before bupropion. Bupropion may cause sudden blurry vision and eye pain ingredients, your doctor likely wont prescribe Contrave before taking in. Bupropion hydrochloride ) extended-release tablets, for oral use its effectiveness, drugs. Hazardous machinery until you know how the medication affects you they include mild to moderate gastrointestinal like... 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Will monitor you closely for the side effects while taking the drug could cause allergic! Hypersensitivity reactions ( frequency unknown ) heart as it passed through to out. Hungry, Contrave may not do much to reduce that hunger, 2 are major, 222 are,... Interactions that can occur with Contrave, talk with your doctor will monitor you closely for the of! Ingredients of bupropion hydrochloride ) extended-release tablets, for oral use obese person, weight loss for.